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Astrocytic CCAAT/Enhancer Binding Protein δ Regulates Neuronal Viability and Spatial Learning Ability via miR-135a

The progression of Alzheimer’s disease (AD) has been associated with astrocytes-induced neuroinflammation. However, the detailed mechanism of astrocytes associated with learning impairments and neuronal loss in AD is poorly defined. Here, we provide novel evidences that astrocytic miR-135a is critic...

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Detalles Bibliográficos
Autores principales: Chu, Yu-Yi, Ko, Chiung-Yuan, Wang, Wei-Jan, Wang, Shao-Ming, Gean, Po-Wu, Kuo, Yu-Min, Wang, Ju-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937099/
https://www.ncbi.nlm.nih.gov/pubmed/26208701
http://dx.doi.org/10.1007/s12035-015-9359-z