Oral absorption profiles of sulfonamides in Shiba goats: a comparison among sulfadimidine, sulfadiazine and sulfanilamide

The oral pharmacokinetics of three sulfonamides, sulfadimidine (pKa 7.5), sulfadiazine (pKa 6.5) and sulfanilamide (pKa 10.5), with different rates of unionization in rumen juice, were compared in Shiba goats to clarify the relationship between drug absorption profiles after their oral administratio...

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Detalles Bibliográficos
Autores principales: ELBADAWY, Mohamed, ISHIHARA, Yusuke, ABOUBAKR, Mohamed, SASAKI, Kazuaki, SHIMODA, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937137/
https://www.ncbi.nlm.nih.gov/pubmed/27010464
http://dx.doi.org/10.1292/jvms.15-0601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937137/
https://www.ncbi.nlm.nih.gov/pubmed/27010464
http://dx.doi.org/10.1292/jvms.15-0601

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