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Inferring gene targets of drugs and chemical compounds from gene expression profiles

Motivation: Finding genes which are directly perturbed or targeted by drugs is of great interest and importance in drug discovery. Several network filtering methods have been created to predict the gene targets of drugs from gene expression data based on an ordinary differential equation model of th...

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Detalles Bibliográficos
Autores principales: Noh, Heeju, Gunawan, Rudiyanto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937192/
https://www.ncbi.nlm.nih.gov/pubmed/27153589
http://dx.doi.org/10.1093/bioinformatics/btw148