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Inferring gene targets of drugs and chemical compounds from gene expression profiles
Motivation: Finding genes which are directly perturbed or targeted by drugs is of great interest and importance in drug discovery. Several network filtering methods have been created to predict the gene targets of drugs from gene expression data based on an ordinary differential equation model of th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937192/ https://www.ncbi.nlm.nih.gov/pubmed/27153589 http://dx.doi.org/10.1093/bioinformatics/btw148 |