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The proneurotrophin receptor sortilin is required for Mycobacterium tuberculosis control by macrophages

Sorting of luminal and membrane proteins into phagosomes is critical for the immune function of this organelle. However, little is known about the mechanisms that contribute to the spatiotemporal regulation of this process. Here, we investigated the role of the proneurotrophin receptor sortilin duri...

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Detalles Bibliográficos
Autores principales: Vázquez, Cristina L., Rodgers, Angela, Herbst, Susanne, Coade, Stephen, Gronow, Achim, Guzman, Carlos A., Wilson, Mark S., Kanzaki, Makoto, Nykjaer, Anders, Gutierrez, Maximiliano G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937236/
https://www.ncbi.nlm.nih.gov/pubmed/27389464
http://dx.doi.org/10.1038/srep29332