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High‐Fat‐Diet Intake Enhances Cerebral Amyloid Angiopathy and Cognitive Impairment in a Mouse Model of Alzheimer's Disease, Independently of Metabolic Disorders

BACKGROUND: The high‐fat Western diet is postulated to be associated with the onset and progression of Alzheimer's disease (AD). However, the role of high‐fat‐diet consumption in AD pathology is unknown. This study was undertaken to examine the role of high‐fat‐diet intake in AD. METHODS AND RE...

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Detalles Bibliográficos
Autores principales: Lin, Bowen, Hasegawa, Yu, Takane, Koki, Koibuchi, Nobutaka, Cao, Cheng, Kim‐Mitsuyama, Shokei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937262/
https://www.ncbi.nlm.nih.gov/pubmed/27412896
http://dx.doi.org/10.1161/JAHA.115.003154