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The Hsp70 homolog Ssb and the 14-3-3 protein Bmh1 jointly regulate transcription of glucose repressed genes in Saccharomyces cerevisiae

Chaperones of the Hsp70 family interact with a multitude of newly synthesized polypeptides and prevent their aggregation. Saccharomyces cerevisiae cells lacking the Hsp70 homolog Ssb suffer from pleiotropic defects, among others a defect in glucose-repression. The highly conserved heterotrimeric kin...

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Detalles Bibliográficos
Autores principales: Hübscher, Volker, Mudholkar, Kaivalya, Chiabudini, Marco, Fitzke, Edith, Wölfle, Tina, Pfeifer, Dietmar, Drepper, Friedel, Warscheid, Bettina, Rospert, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937304/
https://www.ncbi.nlm.nih.gov/pubmed/27001512
http://dx.doi.org/10.1093/nar/gkw168