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RNA folding pathways in stop motion

We introduce a method for predicting RNA folding pathways, with an application to the most important RNA tetraloops. The method is based on the idea that ensembles of three-dimensional fragments extracted from high-resolution crystal structures are heterogeneous enough to describe metastable as well...

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Detalles Bibliográficos
Autores principales: Bottaro, Sandro, Gil-Ley, Alejandro, Bussi, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937309/
https://www.ncbi.nlm.nih.gov/pubmed/27091499
http://dx.doi.org/10.1093/nar/gkw239