Translocation and deletion breakpoints in cancer genomes are associated with potential non-B DNA-forming sequences

Gross chromosomal rearrangements (including translocations, deletions, insertions and duplications) are a hallmark of cancer genomes and often create oncogenic fusion genes. An obligate step in the generation of such gross rearrangements is the formation of DNA double-strand breaks (DSBs). Since the...

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Detalles Bibliográficos
Autores principales: Bacolla, Albino, Tainer, John A., Vasquez, Karen M., Cooper, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937311/
https://www.ncbi.nlm.nih.gov/pubmed/27084947
http://dx.doi.org/10.1093/nar/gkw261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937311/
https://www.ncbi.nlm.nih.gov/pubmed/27084947
http://dx.doi.org/10.1093/nar/gkw261

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