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Translocation and deletion breakpoints in cancer genomes are associated with potential non-B DNA-forming sequences
Gross chromosomal rearrangements (including translocations, deletions, insertions and duplications) are a hallmark of cancer genomes and often create oncogenic fusion genes. An obligate step in the generation of such gross rearrangements is the formation of DNA double-strand breaks (DSBs). Since the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937311/ https://www.ncbi.nlm.nih.gov/pubmed/27084947 http://dx.doi.org/10.1093/nar/gkw261 |