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Two sets of RNAi components are required for heterochromatin formation in trans triggered by truncated transgenes

Across kingdoms, RNA interference (RNAi) has been shown to control gene expression at the transcriptional- or the post-transcriptional level. Here, we describe a mechanism which involves both aspects: truncated transgenes, which fail to produce intact mRNA, induce siRNA accumulation and silencing of...

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Detalles Bibliográficos
Autores principales: Götz, Ulrike, Marker, Simone, Cheaib, Miriam, Andresen, Karsten, Shrestha, Simon, Durai, Dilip A., Nordström, Karl J., Schulz, Marcel H., Simon, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937312/
https://www.ncbi.nlm.nih.gov/pubmed/27085807
http://dx.doi.org/10.1093/nar/gkw267