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Two sets of RNAi components are required for heterochromatin formation in trans triggered by truncated transgenes
Across kingdoms, RNA interference (RNAi) has been shown to control gene expression at the transcriptional- or the post-transcriptional level. Here, we describe a mechanism which involves both aspects: truncated transgenes, which fail to produce intact mRNA, induce siRNA accumulation and silencing of...
Autores principales: | Götz, Ulrike, Marker, Simone, Cheaib, Miriam, Andresen, Karsten, Shrestha, Simon, Durai, Dilip A., Nordström, Karl J., Schulz, Marcel H., Simon, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937312/ https://www.ncbi.nlm.nih.gov/pubmed/27085807 http://dx.doi.org/10.1093/nar/gkw267 |
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