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A fast and powerful W-test for pairwise epistasis testing

Epistasis plays an essential role in the development of complex diseases. Interaction methods face common challenge of seeking a balance between persistent power, model complexity, computation efficiency, and validity of identified bio-markers. We introduce a novel W-test to identify pairwise epista...

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Detalles Bibliográficos
Autores principales: Wang, Maggie Haitian, Sun, Rui, Guo, Junfeng, Weng, Haoyi, Lee, Jack, Hu, Inchi, Sham, Pak Chung, Zee, Benny Chung-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937324/
https://www.ncbi.nlm.nih.gov/pubmed/27112568
http://dx.doi.org/10.1093/nar/gkw347