Sequence-dependent nanometer-scale conformational dynamics of individual RecBCD–DNA complexes

RecBCD is a multifunctional enzyme that possesses both helicase and nuclease activities. To gain insight into the mechanism of its helicase function, RecBCD unwinding at low adenosine triphosphate (ATP) (2–4 μM) was measured using an optical-trapping assay featuring 1 base-pair (bp) precision. Inste...

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Detalles Bibliográficos
Autores principales: Carter, Ashley R., Seaberg, Maasa H., Fan, Hsiu-Fang, Sun, Gang, Wilds, Christopher J., Li, Hung-Wen, Perkins, Thomas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937329/
https://www.ncbi.nlm.nih.gov/pubmed/27220465
http://dx.doi.org/10.1093/nar/gkw445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937329/
https://www.ncbi.nlm.nih.gov/pubmed/27220465
http://dx.doi.org/10.1093/nar/gkw445

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