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The effect of leaving groups on binding and reactivity in enzyme-free copying of DNA and RNA
The template-directed incorporation of nucleotides at the terminus of a growing primer is the basis of the transmission of genetic information. Nature uses polymerases-catalyzed reactions, but enzyme-free versions exist that employ nucleotides with organic leaving groups. The leaving group affects y...
Autores principales: | Kervio, Eric, Sosson, Marilyne, Richert, Clemens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937335/ https://www.ncbi.nlm.nih.gov/pubmed/27235418 http://dx.doi.org/10.1093/nar/gkw476 |
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