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Neuronal TRPV1 activation regulates alveolar bone resorption by suppressing osteoclastogenesis via CGRP

The transient receptor potential vanilloid 1 (TRPV1) channel is abundantly expressed in peripheral sensory neurons where it acts as an important polymodal cellular sensor for heat, acidic pH, capsaicin, and other noxious stimuli. The oral cavity is densely innervated by afferent sensory neurons and...

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Detalles Bibliográficos
Autores principales: Takahashi, Naoki, Matsuda, Yumi, Sato, Keisuke, de Jong, Petrus R., Bertin, Samuel, Tabeta, Koichi, Yamazaki, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937344/
https://www.ncbi.nlm.nih.gov/pubmed/27388773
http://dx.doi.org/10.1038/srep29294