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Transgenic Eimeria tenella as a vaccine vehicle: expressing TgSAG1 elicits protective immunity against Toxoplasma gondii infections in chickens and mice

The surface antigen 1 of Toxoplasma gondii (TgSAG1) is a major immunodominant antigen and is widely considered an ideal candidate for the development of an effective recombinant vaccine against toxoplasmosis. Eimeria tenella, an affinis apicomplexan parasite with T. gondii, is a potential vaccine ve...

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Detalles Bibliográficos
Autores principales: Tang, Xinming, Yin, Guangwen, Qin, Mei, Tao, Geru, Suo, Jingxia, Liu, Xianyong, Suo, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937369/
https://www.ncbi.nlm.nih.gov/pubmed/27387302
http://dx.doi.org/10.1038/srep29379