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CpsR, a GntR family regulator, transcriptionally regulates capsular polysaccharide biosynthesis and governs bacterial virulence in Streptococcus pneumoniae

Transcriptional regulation of capsule expression is critical for pneumococcal transition from carriage to infection, yet the underlying mechanism remains incompletely understood. Here, we describe the regulation of capsular polysaccharide, one of the most important pneumococcal virulence factor by a...

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Detalles Bibliográficos
Autores principales: Wu, Kaifeng, Xu, Hongmei, Zheng, Yuqiang, Wang, Libin, Zhang, Xuemei, Yin, Yibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937376/
https://www.ncbi.nlm.nih.gov/pubmed/27386955
http://dx.doi.org/10.1038/srep29255