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Assembly PCR synthesis of optimally designed, compact, multi-responsive promoters suited to gene therapy application

Gene therapy has the potential to provide innovative treatments for genetic and non-genetic diseases, with the ability to auto-regulate expression levels of therapeutic molecules so that they are produced locally and in direct response to disease activity. Generating disease responsive gene therapy...

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Detalles Bibliográficos
Autores principales: Mohamed, H., Chernajovsky, Y., Gould, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937410/
https://www.ncbi.nlm.nih.gov/pubmed/27387837
http://dx.doi.org/10.1038/srep29388