Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis

Osteoarthritis (OA) is a progressive degenerative disease of articular cartilage and surrounding tissues, and is associated with both advanced age and joint injury. Biomechanical factors play a critical role in the onset and progression of OA, yet the mechanisms through which physiologic or patholog...

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Detalles Bibliográficos
Autores principales: O’Conor, Christopher J., Ramalingam, Sendhilnathan, Zelenski, Nicole A., Benefield, Halei C., Rigo, Isaura, Little, Dianne, Wu, Chia-Lung, Chen, Di, Liedtke, Wolfgang, McNulty, Amy L., Guilak, Farshid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937413/
https://www.ncbi.nlm.nih.gov/pubmed/27388701
http://dx.doi.org/10.1038/srep29053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937413/
https://www.ncbi.nlm.nih.gov/pubmed/27388701
http://dx.doi.org/10.1038/srep29053

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