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Longitudinal live imaging of retinal α-synuclein::GFP deposits in a transgenic mouse model of Parkinson’s Disease/Dementia with Lewy Bodies
Abnormal α-synuclein (α-syn) accumulation in the CNS may underlie neuronal cell and synaptic dysfunction leading to motor and cognitive deficits in synucleinopathies including Parkinson’s disease (PD) and Dementia with Lewy Bodies (DLB). Multiple groups demonstrated α-syn accumulation in CNS accesso...
Autores principales: | Price, Diana L., Rockenstein, Edward, Mante, Michael, Adame, Anthony, Overk, Cassia, Spencer, Brian, Duong-Polk, Karen X., Bonhaus, Douglas, Lindsey, James, Masliah, Eliezer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937425/ https://www.ncbi.nlm.nih.gov/pubmed/27389831 http://dx.doi.org/10.1038/srep29523 |
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