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Loss of tumorigenic potential upon transdifferentiation from keratinocytic into melanocytic lineage
Lineage-specific transcription factors determine the cell fate during development. Direct conversion of several cell types into other lineages has been achieved by the overexpression of specific transcription factors. Even cancer cells have been demonstrated to be amenable to transdifferentiation. H...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937495/ https://www.ncbi.nlm.nih.gov/pubmed/27387763 http://dx.doi.org/10.1038/srep28891 |