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Loss of tumorigenic potential upon transdifferentiation from keratinocytic into melanocytic lineage

Lineage-specific transcription factors determine the cell fate during development. Direct conversion of several cell types into other lineages has been achieved by the overexpression of specific transcription factors. Even cancer cells have been demonstrated to be amenable to transdifferentiation. H...

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Detalles Bibliográficos
Autores principales: Fehrenbach, Sabrina, Novak, Daniel, Bernhardt, Mathias, Larribere, Lionel, Boukamp, Petra, Umansky, Viktor, Utikal, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937495/
https://www.ncbi.nlm.nih.gov/pubmed/27387763
http://dx.doi.org/10.1038/srep28891