Cargando…

Uncovering a Dual Regulatory Role for Caspases During Endoplasmic Reticulum Stress-induced Cell Death

Many diseases are associated with endoplasmic reticulum (ER) stress, which results from an accumulation of misfolded proteins. This triggers an adaptive response called the “unfolded protein response” (UPR), and prolonged exposure to ER stress leads to cell death. Caspases are reported to play a cri...

Descripción completa

Detalles Bibliográficos
Autores principales: Anania, Veronica G., Yu, Kebing, Gnad, Florian, Pferdehirt, Rebecca R., Li, Han, Ma, Taylur P., Jeon, Diana, Fortelny, Nikolaus, Forrest, William, Ashkenazi, Avi, Overall, Christopher M., Lill, Jennie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937505/
https://www.ncbi.nlm.nih.gov/pubmed/27125827
http://dx.doi.org/10.1074/mcp.M115.055376