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The Importance of Non-accessible Crosslinks and Solvent Accessible Surface Distance in Modeling Proteins with Restraints From Crosslinking Mass Spectrometry

Crosslinking mass spectrometry (XL-MS) is becoming an increasingly popular technique for modeling protein monomers and complexes. The distance restraints garnered from these experiments can be used alone or as part of an integrative modeling approach, incorporating data from many sources. However, m...

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Detalles Bibliográficos
Autores principales: Bullock, Joshua Matthew Allen, Schwab, Jannik, Thalassinos, Konstantinos, Topf, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937519/
https://www.ncbi.nlm.nih.gov/pubmed/27150526
http://dx.doi.org/10.1074/mcp.M116.058560