The interaction of PRC2 with RNA or chromatin is mutually antagonistic

Polycomb repressive complex 2 (PRC2) modifies chromatin to maintain genes in a repressed state during development. PRC2 is primarily associated with CpG islands at repressed genes and also possesses RNA binding activity. However, the RNAs that bind PRC2 in cells, the subunits that mediate these inte...

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Detalles Bibliográficos
Autores principales: Beltran, Manuel, Yates, Christopher M., Skalska, Lenka, Dawson, Marcus, Reis, Filipa P., Viiri, Keijo, Fisher, Cynthia L., Sibley, Christopher R., Foster, Benjamin M., Bartke, Till, Ule, Jernej, Jenner, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937559/
https://www.ncbi.nlm.nih.gov/pubmed/27197219
http://dx.doi.org/10.1101/gr.197632.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937559/
https://www.ncbi.nlm.nih.gov/pubmed/27197219
http://dx.doi.org/10.1101/gr.197632.115

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