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Quantitative insertion-site sequencing (QIseq) for high throughput phenotyping of transposon mutants
Genetic screening using random transposon insertions has been a powerful tool for uncovering biology in prokaryotes, where whole-genome saturating screens have been performed in multiple organisms. In eukaryotes, such screens have proven more problematic, in part because of the lack of a sensitive a...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937560/ https://www.ncbi.nlm.nih.gov/pubmed/27197223 http://dx.doi.org/10.1101/gr.200279.115 |