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Multikernel linear mixed models for complex phenotype prediction

Linear mixed models (LMMs) and their extensions have recently become the method of choice in phenotype prediction for complex traits. However, LMM use to date has typically been limited by assuming simple genetic architectures. Here, we present multikernel linear mixed model (MKLMM), a predictive mo...

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Detalles Bibliográficos
Autores principales: Weissbrod, Omer, Geiger, Dan, Rosset, Saharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937570/
https://www.ncbi.nlm.nih.gov/pubmed/27302636
http://dx.doi.org/10.1101/gr.201996.115