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The eicosanoids leukotriene D(4) and prostaglandin E(2) promote the tumorigenicity of colon cancer-initiating cells in a xenograft mouse model
BACKGROUND: Colorectal cancer is one of the most common types of cancers worldwide. Recent studies have identified cancer-initiating cells (CICs) as a subgroup of replication-competent cells in the development of colorectal cancer. Although it is understood that an inflammation-rich tumor microenvir...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937611/ https://www.ncbi.nlm.nih.gov/pubmed/27388564 http://dx.doi.org/10.1186/s12885-016-2466-z |