The eicosanoids leukotriene D(4) and prostaglandin E(2) promote the tumorigenicity of colon cancer-initiating cells in a xenograft mouse model

BACKGROUND: Colorectal cancer is one of the most common types of cancers worldwide. Recent studies have identified cancer-initiating cells (CICs) as a subgroup of replication-competent cells in the development of colorectal cancer. Although it is understood that an inflammation-rich tumor microenvir...

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Detalles Bibliográficos
Autores principales: Bellamkonda, Kishan, Chandrashekar, Naveen Kumar, Osman, Janina, Selvanesan, Benson Chellakkan, Savari, Sayeh, Sjölander, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937611/
https://www.ncbi.nlm.nih.gov/pubmed/27388564
http://dx.doi.org/10.1186/s12885-016-2466-z

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