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Interaction potential of Carmegliptin with P-glycoprotein (Pgp) transporter in healthy volunteers

OBJECTIVE: The primary objective of this study was to investigate the interaction potential of carmegliptin with P-glycoprotein transporter in vitro and in vivo. A secondary objective was to investigate the safety and tolerability of carmegliptin alone or co-administered with verapamil. RESEARCH DES...

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Detalles Bibliográficos
Autores principales: Kuhlmann, Olaf, Carlile, David, Noe, Johannes, Bentley, Darren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937633/
https://www.ncbi.nlm.nih.gov/pubmed/27536451
http://dx.doi.org/10.3109/21556660.2014.900065