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Absolute bioavailability and regional absorption of ticagrelor in healthy volunteers

OBJECTIVE: Ticagrelor is a direct-acting, reversibly-binding, oral P2Y(12) receptor antagonist. It demonstrates predictable, linear pharmacokinetics. Two studies were undertaken to further elucidate the absolute bioavailability of ticagrelor and its regional absorption in the gastrointestinal (GI) t...

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Detalles Bibliográficos
Autores principales: Teng, Renli, Maya, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937635/
https://www.ncbi.nlm.nih.gov/pubmed/27536453
http://dx.doi.org/10.3109/21556660.2014.946604