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Identification of metabolites of dalfampridine (4-aminopyridine) in dog and rat
BACKGROUND: Dalfampridine (4-aminopyridine; 4-AP) is a potassium channel blocker available in the United States to improve walking in patients with multiple sclerosis as demonstrated by an increase in walking speed. Its pharmacokinetics have been evaluated in human studies but its metabolites are no...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Maney Publishing
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937651/ https://www.ncbi.nlm.nih.gov/pubmed/27536440 http://dx.doi.org/10.3109/21556660.2013.794143 |