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Emerging concepts for PI3K/mTOR inhibition as a potential treatment for osteosarcoma
Patients with metastatic and recurrent osteosarcoma fare poorly, and new therapeutic strategies are needed to improve survival. Several recent complementary genomic and pathway analyses of both murine and human osteosarcoma have revealed common aberrations of the phosphoinositide 3-kinase (PI3K)/mam...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000Research
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937817/ https://www.ncbi.nlm.nih.gov/pubmed/27441088 http://dx.doi.org/10.12688/f1000research.8228.1 |