Histone deacetylase inhibitor sodium butyrate suppresses proliferation and promotes apoptosis in osteosarcoma cells by regulation of the MDM2–p53 signaling

Histone deacetylase inhibitors have been reported to induce tumor cell growth arrest, differentiation, and apoptosis. This study aimed to investigate the effects of one histone deacetylase inhibitor – sodium butyrate (SB) – on osteosarcoma (OS) cell proliferation and apoptosis and also the molecular...

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Detalles Bibliográficos
Autores principales: Xie, Chuhai, Wu, Boyi, Chen, Binwei, Shi, Qunwei, Guo, Jianhong, Fan, Ziwen, Huang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938147/
https://www.ncbi.nlm.nih.gov/pubmed/27445491
http://dx.doi.org/10.2147/OTT.S105418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938147/
https://www.ncbi.nlm.nih.gov/pubmed/27445491
http://dx.doi.org/10.2147/OTT.S105418

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