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NDUFAF5 Hydroxylates NDUFS7 at an Early Stage in the Assembly of Human Complex I

Complex I (NADH ubiquinone oxidoreductase) in mammalian mitochondria is an L-shaped assembly of 45 proteins. One arm lies in the inner membrane, and the other extends about 100 Å into the matrix of the organelle. The extrinsic arm contains binding sites for NADH, the primary electron acceptor FMN, a...

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Detalles Bibliográficos
Autores principales: Rhein, Virginie F., Carroll, Joe, Ding, Shujing, Fearnley, Ian M., Walker, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938201/
https://www.ncbi.nlm.nih.gov/pubmed/27226634
http://dx.doi.org/10.1074/jbc.M116.734970