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Low Serum Complement C3 Levels at Diagnosis of Renal ANCA-Associated Vasculitis Is Associated with Poor Prognosis

BACKGROUND: Recent studies have demonstrated the key role of the complement alternative pathway (cAP) in the pathophysiology of experimental ANCA-associated vasculitis (AAV). However, in human AAV the role of cAP has not been extensively explored. In the present work, we analysed circulating serum C...

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Detalles Bibliográficos
Autores principales: Augusto, Jean-François, Langs, Virginie, Demiselle, Julien, Lavigne, Christian, Brilland, Benoit, Duveau, Agnès, Poli, Caroline, Chevailler, Alain, Croue, Anne, Tollis, Frederic, Sayegh, Johnny, Subra, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938207/
https://www.ncbi.nlm.nih.gov/pubmed/27391243
http://dx.doi.org/10.1371/journal.pone.0158871