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Deep Whole-Genome Sequencing to Detect Mixed Infection of Mycobacterium tuberculosis

Mixed infection by multiple Mycobacterium tuberculosis (MTB) strains is associated with poor treatment outcome of tuberculosis (TB). Traditional genotyping methods have been used to detect mixed infections of MTB, however, their sensitivity and resolution are limited. Deep whole-genome sequencing (W...

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Detalles Bibliográficos
Autores principales: Gan, Mingyu, Liu, Qingyun, Yang, Chongguang, Gao, Qian, Luo, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938208/
https://www.ncbi.nlm.nih.gov/pubmed/27391214
http://dx.doi.org/10.1371/journal.pone.0159029