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Deep Whole-Genome Sequencing to Detect Mixed Infection of Mycobacterium tuberculosis
Mixed infection by multiple Mycobacterium tuberculosis (MTB) strains is associated with poor treatment outcome of tuberculosis (TB). Traditional genotyping methods have been used to detect mixed infections of MTB, however, their sensitivity and resolution are limited. Deep whole-genome sequencing (W...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938208/ https://www.ncbi.nlm.nih.gov/pubmed/27391214 http://dx.doi.org/10.1371/journal.pone.0159029 |