Pharmacophore modeling and in silico toxicity assessment of potential anticancer agents from African medicinal plants

Molecular modeling has been employed in the search for lead compounds of chemotherapy to fight cancer. In this study, pharmacophore models have been generated and validated for use in virtual screening protocols for eight known anticancer drug targets, including tyrosine kinase, protein kinase B β,...

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Detalles Bibliográficos
Autores principales: Ntie-Kang, Fidele, Simoben, Conrad Veranso, Karaman, Berin, Ngwa, Valery Fuh, Judson, Philip Neville, Sippl, Wolfgang, Mbaze, Luc Meva’a
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938243/
https://www.ncbi.nlm.nih.gov/pubmed/27445461
http://dx.doi.org/10.2147/DDDT.S108118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938243/
https://www.ncbi.nlm.nih.gov/pubmed/27445461
http://dx.doi.org/10.2147/DDDT.S108118

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