A plant-expressed conjugate vaccine breaks CD4(+) tolerance and induces potent immunity against metastatic Her2(+) breast cancer

Passive antibody therapy for cancer is an effective but costly treatment modality. Induction of therapeutically potent anticancer antibodies by active vaccination is an attractive alternative but has proven challenging in cancer due to tolerogenic pressure in patients. Here, we used the clinically r...

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Detalles Bibliográficos
Autores principales: Chotprakaikiat, Warayut, Allen, Alex, Bui-Minh, Duc, Harden, Elena, Jobsri, Jantipa, Cavallo, Federica, Gleba, Yuri, Stevenson, Freda K., Ottensmeier, Christian, Klimyuk, Victor, Savelyeva, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938312/
https://www.ncbi.nlm.nih.gov/pubmed/27471642
http://dx.doi.org/10.1080/2162402X.2016.1166323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938312/
https://www.ncbi.nlm.nih.gov/pubmed/27471642
http://dx.doi.org/10.1080/2162402X.2016.1166323

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