Calcium Influx of Mast Cells Is Inhibited by Aptamers Targeting the First Extracellular Domain of Orai1

Using the systematic evolution of ligands by exponential enrichment (SELEX) method, we identified oligonucleotides that bind to the first extracellular domain of the Orai1 protein with high affinities and high specificities. These ligands were isolated from a random single-strand DNA (ssDNA) library...

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Detalles Bibliográficos
Autores principales: Sun, Renshan, Yang, Yongqiang, Ran, Xinze, Yang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938386/
https://www.ncbi.nlm.nih.gov/pubmed/27390850
http://dx.doi.org/10.1371/journal.pone.0158223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938386/
https://www.ncbi.nlm.nih.gov/pubmed/27390850
http://dx.doi.org/10.1371/journal.pone.0158223

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