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Sodium Thiosulfate Prevents Chondrocyte Mineralization and Reduces the Severity of Murine Osteoarthritis

OBJECTIVES: Calcium-containing crystals participate in the pathogenesis of OA. Sodium thiosulfate (STS) has been shown to be an effective treatment in calcification disorders such as calciphylaxis and vascular calcification. This study investigated the effects and mechanisms of action of STS in a mu...

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Detalles Bibliográficos
Autores principales: Nasi, Sonia, Ea, Hang-Korng, Lioté, Frédéric, So, Alexander, Busso, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938519/
https://www.ncbi.nlm.nih.gov/pubmed/27391970
http://dx.doi.org/10.1371/journal.pone.0158196