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Exposure of Human Lung Cells to Tobacco Smoke Condensate Inhibits the Nucleotide Excision Repair Pathway

Exposure to tobacco smoke is the number one risk factor for lung cancer. Although the DNA damaging properties of tobacco smoke have been well documented, relatively few studies have examined its effect on DNA repair pathways. This is especially true for the nucleotide excision repair (NER) pathway w...

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Detalles Bibliográficos
Autores principales: Holcomb, Nathaniel, Goswami, Mamta, Han, Sung Gu, Clark, Samuel, Orren, David K., Gairola, C. Gary, Mellon, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938567/
https://www.ncbi.nlm.nih.gov/pubmed/27391141
http://dx.doi.org/10.1371/journal.pone.0158858