Co-Culture of Tumor Spheroids and Fibroblasts in a Collagen Matrix-Incorporated Microfluidic Chip Mimics Reciprocal Activation in Solid Tumor Microenvironment

Multicellular 3D culture and interaction with stromal components are considered essential elements in establishing a ‘more clinically relevant’ tumor model. Matrix-embedded 3D cultures using a microfluidic chip platform can recapitulate the microscale interaction within tumor microenvironments. As a...

Descripción completa

Detalles Bibliográficos
Autores principales: Jeong, Su-Yeong, Lee, Ji-Hyun, Shin, Yoojin, Chung, Seok, Kuh, Hyo-Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938568/
https://www.ncbi.nlm.nih.gov/pubmed/27391808
http://dx.doi.org/10.1371/journal.pone.0159013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938568/
https://www.ncbi.nlm.nih.gov/pubmed/27391808
http://dx.doi.org/10.1371/journal.pone.0159013

Ejemplares similares