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Co-Culture of Tumor Spheroids and Fibroblasts in a Collagen Matrix-Incorporated Microfluidic Chip Mimics Reciprocal Activation in Solid Tumor Microenvironment

Multicellular 3D culture and interaction with stromal components are considered essential elements in establishing a ‘more clinically relevant’ tumor model. Matrix-embedded 3D cultures using a microfluidic chip platform can recapitulate the microscale interaction within tumor microenvironments. As a...

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Detalles Bibliográficos
Autores principales:	Jeong, Su-Yeong, Lee, Ji-Hyun, Shin, Yoojin, Chung, Seok, Kuh, Hyo-Jeong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938568/ https://www.ncbi.nlm.nih.gov/pubmed/27391808 http://dx.doi.org/10.1371/journal.pone.0159013

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