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Comprehensive Analysis of Genome Rearrangements in Eight Human Malignant Tumor Tissues

Carcinogenesis is a complex multifactorial, multistage process, but the precise mechanisms are not well understood. In this study, we performed a genome-wide analysis of the copy number variation (CNV), breakpoint region (BPR) and fragile sites in 2,737 tumor samples from eight tumor entities and in...

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Detalles Bibliográficos
Autores principales: Marczok, Stefanie, Bortz, Birgit, Wang, Chong, Pospisil, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938598/
https://www.ncbi.nlm.nih.gov/pubmed/27391163
http://dx.doi.org/10.1371/journal.pone.0158995