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Placental Hypomethylation Is More Pronounced in Genomic Loci Devoid of Retroelements

The human placenta is hypomethylated compared to somatic tissues. However, the degree and specificity of placental hypomethylation across the genome is unclear. We assessed genome-wide methylation of the human placenta and compared it to that of the neutrophil, a representative homogeneous somatic c...

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Detalles Bibliográficos
Autores principales: Chatterjee, Aniruddha, Macaulay, Erin C., Rodger, Euan J., Stockwell, Peter A., Parry, Matthew F., Roberts, Hester E., Slatter, Tania L., Hung, Noelyn A., Devenish, Celia J., Morison, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938645/
https://www.ncbi.nlm.nih.gov/pubmed/27172225
http://dx.doi.org/10.1534/g3.116.030379