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Placental Hypomethylation Is More Pronounced in Genomic Loci Devoid of Retroelements
The human placenta is hypomethylated compared to somatic tissues. However, the degree and specificity of placental hypomethylation across the genome is unclear. We assessed genome-wide methylation of the human placenta and compared it to that of the neutrophil, a representative homogeneous somatic c...
Autores principales: | Chatterjee, Aniruddha, Macaulay, Erin C., Rodger, Euan J., Stockwell, Peter A., Parry, Matthew F., Roberts, Hester E., Slatter, Tania L., Hung, Noelyn A., Devenish, Celia J., Morison, Ian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938645/ https://www.ncbi.nlm.nih.gov/pubmed/27172225 http://dx.doi.org/10.1534/g3.116.030379 |
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