Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients

Multiple sclerosis (MS) is a prevalent neurological disease of complex etiology. Here, we describe the characterization of a multi-incident MS family that nominated a rare missense variant (p.G420D) in plasminogen (PLG) as a putative genetic risk factor for MS. Genotyping of PLG p.G420D (rs139071351...

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Detalles Bibliográficos
Autores principales: Sadovnick, A. Dessa, Traboulsee, Anthony L., Bernales, Cecily Q., Ross, Jay P., Forwell, Amanda L., Yee, Irene M., Guillot-Noel, Lena, Fontaine, Bertrand, Cournu-Rebeix, Isabelle, Alcina, Antonio, Fedetz, Maria, Izquierdo, Guillermo, Matesanz, Fuencisla, Hilven, Kelly, Dubois, Bénédicte, Goris, An, Astobiza, Ianire, Alloza, Iraide, Antigüedad, Alfredo, Vandenbroeck, Koen, Akkad, Denis A., Aktas, Orhan, Blaschke, Paul, Buttmann, Mathias, Chan, Andrew, Epplen, Joerg T., Gerdes, Lisa-Ann, Kroner, Antje, Kubisch, Christian, Kümpfel, Tania, Lohse, Peter, Rieckmann, Peter, Zettl, Uwe K., Zipp, Frauke, Bertram, Lars, Lill, Christina M, Fernandez, Oscar, Urbaneja, Patricia, Leyva, Laura, Alvarez-Cermeño, Jose Carlos, Arroyo, Rafael, Garagorri, Aroa M., García-Martínez, Angel, Villar, Luisa M., Urcelay, Elena, Malhotra, Sunny, Montalban, Xavier, Comabella, Manuel, Berger, Thomas, Fazekas, Franz, Reindl, Markus, Schmied, Mascha C., Zimprich, Alexander, Vilariño-Güell, Carles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938660/
https://www.ncbi.nlm.nih.gov/pubmed/27194806
http://dx.doi.org/10.1534/g3.116.030841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938660/
https://www.ncbi.nlm.nih.gov/pubmed/27194806
http://dx.doi.org/10.1534/g3.116.030841

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