The Rate and Spectrum of Spontaneous Mutations in Mycobacterium smegmatis, a Bacterium Naturally Devoid of the Postreplicative Mismatch Repair Pathway

Mycobacterium smegmatis is a bacterium that is naturally devoid of known postreplicative DNA mismatch repair (MMR) homologs, mutS and mutL, providing an opportunity to investigate how the mutation rate and spectrum has evolved in the absence of a highly conserved primary repair pathway. Mutation acc...

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Detalles Bibliográficos
Autores principales: Kucukyildirim, Sibel, Long, Hongan, Sung, Way, Miller, Samuel F., Doak, Thomas G., Lynch, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938668/
https://www.ncbi.nlm.nih.gov/pubmed/27194804
http://dx.doi.org/10.1534/g3.116.030130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938668/
https://www.ncbi.nlm.nih.gov/pubmed/27194804
http://dx.doi.org/10.1534/g3.116.030130

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