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The Rate and Spectrum of Spontaneous Mutations in Mycobacterium smegmatis, a Bacterium Naturally Devoid of the Postreplicative Mismatch Repair Pathway
Mycobacterium smegmatis is a bacterium that is naturally devoid of known postreplicative DNA mismatch repair (MMR) homologs, mutS and mutL, providing an opportunity to investigate how the mutation rate and spectrum has evolved in the absence of a highly conserved primary repair pathway. Mutation acc...
Autores principales: | Kucukyildirim, Sibel, Long, Hongan, Sung, Way, Miller, Samuel F., Doak, Thomas G., Lynch, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938668/ https://www.ncbi.nlm.nih.gov/pubmed/27194804 http://dx.doi.org/10.1534/g3.116.030130 |
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